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One clinical series found pain relief in 7 of 12 patients after a single intraarticular knee injection [4]

Running them together is expected to make these effects more frequent and more intense during the co-escalation phase (roughly weeks 9-20 in the staggered protocol)

Nat Commun 12 , 470, doi:10.1038/s41467-020-20790-0 (2021)

If the pancreas becomes inflamed (which is referred to as pancreatitis), these digestive enzymes may become overactive and start breaking down the pancreas itself, along with surrounding organs like the liver and small intestine

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