Effect on the Gastrointestinal Absorption of Drugs from Different Classes in the Biopharmaceutics Classification System, When Treating with Liraglutide
Intraepithelial lymphocytes (IELs), a distinct lineage of T cells residing within the epithelial layer, express high levels of GLP-1 receptors
So the lines between 10 and 20 represent 12, 14, 16, and 18 units
The equivalent injectable dose would therefore be approximately 2mg to 2.4mg weekly, since injectable bioavailability approaches 100%
So overall, twice the effort is needed to build the advantage and half as much to destroy it or return it. The study, published in BMJ Medicine, underscores the need to maintain GLP-1 therapy to continue receiving its cardiovascular benefits
Biol Reprod (2016) 94(6):127