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Longer-acting weekly formulations like semaglutide and dulaglutide reach steady-state concentrations more slowly than daily preparations but may offer more consistent effects
No changes in plasma cholesterol levels were observed for any of the treatments (Fig
Patients should report any new or worsening mood symptoms to their healthcare provider promptly
Additionally, GLP-1 drugs have been shown to lower the risk of major cardiovascular events, such as heart attacks and strokes, in patients with type 2 diabetes, regardless of their impact on blood sugar levels
It is true that normally when cutting back on calories and fat, our body stores fat and our metabolism slows down
If a patient on semaglutide 2.4 mg (Wegovy) has not met that threshold after 16 weeks, switching to tirzepatide is a reasonable next step supported by that guideline framework
