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You're concerned about signs of aging (fine lines, wrinkles, loss of firmness)
Because it is found in high concentrations in the blood and muscle tissue, it acts as a versatile "workhorse" for various metabolic processes
This is due to saturation of the IGF-1R receptors, resulting in the remaining IGF-1 circulating in the blood attaching to bone and gastrointestinal tissue [1, 16]
doi: 10.1038/nature20117 17 GagnonEDuclosSRondeauCChevetECameronPHSteele-MortimerOet al
Data regarding a study on bone mineral density (BMD) and bone mineral content (BMC) in 11 female participants aged 710 years found that higher plasma IGF-1 DES concentrations were correlated with superior BMD and BMC [14]