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These limitations notwithstanding, our theory reveals major potential benefits of moving beyond the confines of once-weekly dosing of incretin mimetics, offering significant value for patients, physicians, insurers, and governments

That could be another reason why eye disease didnt appear to worsen as much in our study. Historically, patients with diabetes who have used insulin resulting in dramatic drops in HbA1c more often have reported worsening diabetic retinopathy, she notes