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The bioavailability of GLP-1 RAs administered orally alone is very low and, in order to avoid degradation, the active molecule has to be protected and delivered through the GI epithelium and into the bloodstream
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For someone weighing 200 pounds, a 15% reduction would be about 30 pounds
However, I think it applies poorly and the pencil is "dry" when applying the product to the lips
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