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Description

The Optical Coherence Tomography work by Hubinger and colleagues documented that microneedle-induced channels close measurably within hours of insertion, with full barrier restoration on the order of 24 hours for shallow channels [4]

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Since mitochondria do not have the enzymes involved in the synthesis of GSH, all the GSH found in the mitochondrial compartment comes from the cytosol

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Given this fact, ART toxicity needs to be analyzed thoroughly, since side effects can accumulate over time and cause serious repercussions to patients, including dysfunction of the BBB (Fig

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