In addition, excessive androgen receptor activation alters transcriptional regulation of genes involved in glucose and lipid metabolism, thereby promoting hepatic steatosis and insulin resistance (72)
For patients already using a GLP-1 receptor agonist but needing stronger blood sugar and weight control, tirzepatide may offer added benefits because of its dual-action mechanism
Hardan AY, Fung LK, Libove RA, et al
Walsh GL, Gokaslan ZL, McCutcheon IE, Mineo MT, Yasko AW, Swisher SG , Schrump DS, Nesbitt JC, Putnam JB Jr, Roth JA
Ma S, Dielschneider RF, Henson ES, Xiao W, Choquette TR, Blankstein AR, et al
Moderate vs