As a naturally occurring antioxidant, it helps neutralize toxins, brighten the skin by reducing melanin production, and protect against early signs of aging
Regardless of whether you consume a triple cheeseburger or a supplement, it is natural to question any potential negative effects on your body
Another factor to consider is the pharmacy where you obtain your prescription meds
While these mechanisms are well-documented in general skin-brightening studies, the application for those with localized depigmentation is more complex
When released to the circulation, the bone-derived FGF23 binds to its receptor in epithelial cells of the proximal tubules of the kidney leading to decreased expression the type II sodium-phosphate co-transporters, NPT2a (encoded by the SLC34A1 gene) and NPT2c (encoded by the SLC34A3 gene)
GAPDH and Histone-H3 served as loading controls