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Some individuals may struggle to absorb B12 through diet alone especially those with certain dietary restrictions or medical conditions

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Intramuscular (IM) B12 injections using hydroxocobalamin, the preferred licensed form in the UK are recommended when: Oral supplementation has failed to correct a documented deficiency The patient has difficulty adhering to daily oral regimens Serum B12 levels remain persistently low despite adequate oral dosing There is clinical evidence of neurological or haematological complications In line with BNF guidance, the standard IM regimen for confirmed deficiency without neurological involvement is a loading course of 1 mg hydroxocobalamin on alternate days for two weeks , followed by maintenance of 1 mg every three months

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TIER PLANS TIER 1 (5mg total) $195 total for 8-10 week supply Monthly cost breakdown: $78-$97 based on weekly dose Recommended if new to treatment or for those on 0.2-0.6mg/week TIER 2 (10mg total) $230 total for 8-10 week supply Monthly cost breakdown: $92-$115 based on weekly dose Recommended for those on 0.7-1.2mg/week TIER 3 (20mg total) $260 total for 8-10 week supply Monthly cost breakdown: $104-$130 based on weekly dose Recommended for those on 1.3mg/week and up TIER 4* (30mg total) $300 total for 8-10 week supply For patients approved to be on high dose therapy of 3-4mg per week Monthly cost breakdown: $120-$150 based on weekly dose TIER 5* (40mg total) $350 total for 8-10 week supply For patients approved to be on high dose therapy of 4-5mg per week Monthly cost breakdown: $140-$175 based on weekly dose Southend Pharmacy - Semaglutide/B6 Injection Up to 90 days BUD

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