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Joseph Volpicelli, a psychiatrist and addiction-medication researcher in Pennsylvania, the drug can also affect the brain's reward circuit, dulling the dopamine hit someone might otherwise get from a greasy french fry or dirty martini

Incorrect reconstitution can lead to inconsistent dosing, which can make side effects unpredictable

These may include mild discomfort at the injection site or allergic reactions

The preservative systems in compounded formulations are typically less robust than those in manufactured products, meaning room temperature exposure degrades the medication faster

There is no MHRA-approved guidance on how long retatrutide can be kept at room temperature, as it is an unlicensed investigational medicine

A higher strength version of Ozempic has been developed specifically for weight-loss and is marketed as Wegovy