Ruscitti, P
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The STEP-5 trial, published in Nature Medicine, evaluated the long-term efficacy of semaglutide 2.4 mg versus placebo in maintaining weight loss over a 2-year period in 304 participants (5)
Semaglutide-mediated weight loss does not only depend on the drug dose
Week 1: 14 units (0.7 mg) daily Week 2: 16 units (0.8 mg) daily Week 3: 18 units (0.9 mg) daily Week 4: 20 units (1.0 mg) daily Patients using CJC 1295 ipamorelin for weight loss often see fat reduction become noticeable during month two
While exercise isnt required for weight loss with Semaglutide, adding physical activity enhances fat burning and improves long-term success