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Hearing Difficulties and Tinnitus in Construction, Agricultural, Music, and Finance Industries: Contributions of Demographic, Health, and Lifestyle Factors

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In this context, we also demonstrated that the disruption of the cellular redox buffer, controlled by GSH, increases not only the oxidative stress (Filomeni et al., 2005a), but also the endogenous physiological flux of NO in neuronal cells ( S -nitrosylation, and DNA strand breaks in neuronal cells

Relationship of cytosolic glutathione to efflux and mitochondrial sequestration

192 Additionally, mRNA therapy has been applied to treat patients with deficiencies in essential enzyme genes, such as argininosuccinate lyase, ornithine transcarbamylase, and methylmalonyl-CoA mutase (MUT), therefore restoring enzyme levels and mitigating deficiencies

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