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Int J Dev Neurosci
What it does do is reduce appetite and carbohydrate cravings, which makes adhering to a ketogenic diet considerably easier than it would be otherwise
Untreated, those biological changes can increase the risk of a variety of problems like Type 2 diabetes, heart disease and even increase risk for 13 cancers
Retatrutide has consistently higher GI rates than tirzepatide
[1] Additionally, the medication might theoretically influence lower esophageal sphincter function, though this specific effect has not been extensively studied
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