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Meister D, Bode J, et al
A preclinical study on the rescue of normal tissue by nicotinic acid in high-dose treatment with APO866, a specific nicotinamide phosphoribosyltransferase inhibitor
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PMID: 14647006
Elimination of the thiol group by the E2 or E1cb mechanism results in the formation of an -aminoacrylate intermediate ( Vb ) and H 2 S or its anion
In parallel, the C-terminal P37 Cagri contributes to altered dynamics of the ECD protomers in an AMYR-subtype-specific manner
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