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In the withdrawal trial, continuing preserved loss far better than switching to placebo, which regained about 14% over a year. The metabolic benefit fades in proportion to the weight regained, so a taper plus protein and resistance training beats a hard stop

The two compound classes target separate metabolic systems, which is why they appear in different sections of the research literature and the WADA Prohibited List

Always swirl the vial gently until the powder is fully dissolved

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