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The sixth coordination site, the reactive center, is variable, being a cyano group (CN), a hydroxyl group (OH), a methyl group (CH 3 ) or a 5-deoxyadenosyl group
Here the Intrinsic Factor binds to the B12 and the "B12/IF Complex" enters the cells on the wall of the Ileum after binding to receptors on the surface of the Ileal cells, allowing it to enter the blood stream
NAD+ is an oxidizing agent in cellular metabolism, while NADH is a metabolic reducing agent
Specific Adverse Effects Reported in Clinical Trials While the overall safety profile was excellent, clinical trials documented all adverse events regardless of severity or causality
