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Kang S-A, Hasan N, Mann AP, Zheng W, Zhao L, Morris L, et al
The brain-derived neurotrophic factor (BDNF) and its receptor, tyrosine kinase receptor B (TrkB), are essential and common mechanisms for the antidepressant effects of both the parent molecules of ketamines [i.e., S, R()ketamine, S(+)ketamine, and R()ketamine] and their active metabolites [i.e., (2R,6R)-hydroxynorketamine and of S(+)norketamine] (Yang et al., 2019)
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Consequently, if costs remain high, individuals in lower socioeconomic areas with limited health coverage will face significant barriers to accessing these medications, he added
Originally developed to manage blood sugar and support weight loss, these medications are currently being studied for their potential effects on sexual function
