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Curcumin induced the ferroptotic death of breast cancer cells by upregulating HO-1 expression characterized by a marked accumulation of intracellular iron, ROS, lipid peroxides, and the downregulated GSH level (Li R
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Dixon et al., 2012)
Maintaining an adequate GSH redox status and 25-hydroxy-vitamin D levels will have the potential to reduce oxidative stress, enhance immunity and diminish the adverse clinical consequences of COVID-19 especially in African American communities having glucose-6-phosphate dehydrogenase deficiency, enzyme necessary to prevent GSH exhaustion and depletion (Jain and Parsanathan, 2020
Lin SL, Chiang WC, Chen YM, Lai CF, Tsai TJ, Hsieh BS
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