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Methionine serves as a methyl donor in numerous biochemical reactions and is a precursor to S-adenosylmethionine (SAMe), which participates in phospholipid synthesis

However, the magnitude of VEGF change and the upstream signaling pathway driving it are not established with the precision needed to predict dose-response in humans

Weeks 8-12+: More substantial changes for those who persist

These neurological symptoms require urgent medical attention, as prolonged B12 deficiency can lead to irreversible nerve damage

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The synthetic version is sequence-identical to this natural fragment