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Nevertheless, a recent study has shown promising results in PCOS patients with restoration of menstrual cyclicity (lowering testosterone and AMH levels, increasing FSH with no alteration of glycemic or lipid parameters) when administrated at 2mg/day for 6 months (8)
Small amounts of ROS are required for normal sperm functions such as sperm capacitation and acrosome reaction (59)
There is no doubt that the comprehensive understanding of metformins mechanism of action is crucial for its potential application in OA treatment
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Aragon G, Younossi ZM
Tryptophan-derived metabolites, such as indole and its derivatives, influence bacterial biofilm formation and pathogenicity through AhR-mediated pathways, concurrently influencing host immunological responses 47
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