More recent work has confirmed the challenge of enrolling women in some therapeutic areas: in stroke clinical trials, for instance, women have been underrepresented even after incidence and prevalence of the disease is taken into account (Carcel, 2021), with highest underrepresentation reported in secondary prevention trials (10 percent in one study) (Strong et al., 2020)
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Glucagon Receptor Activation and Liver Function Unlike semaglutide or tirzepatide, retatrutide includes glucagon receptor agonism as part of its mechanism
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[3] history of cancer within the past five years