Even with a quick check-in during refills
BPC-157 studies in rodent models have used concentrations ranging widely from nanomolar to micromolar in cell culture, and from 10mcg/kg to 10mg/kg in animal models depending on the study endpoint [1,2]
When Health Canada approves a generic version of a drug, they go through a very rigorous process and ensure that the drug that theyre approving is as close to the original drug chemically as it can possibly be, he said
Kloesch B, Liszt M, Broell J, Steiner G
Needle gauge matters too: a finer needle (commonly 29-31 gauge for insulin syringes) reduces the mechanical stress placed on the solution as it passes through the needle bore compared to a larger-bore needle, and produces a smaller, cleaner puncture through the vial's rubber stopper, reducing the risk of coring small rubber fragments breaking off into the solution
This effect is part of the entero-insular axis of glucose homeostasis and is estimated to be responsible for at least 50% of insulin secretion [2, 3]