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The results indicated lipid-lowering potential with combined therapy of alogliptin [54]

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Elevated ROS levels sustained activation of the ATR-Chk1 pathway, which in turn contributed to cisplatin resistance in ovarian cancer cells (41)

Measurement of GSH and GSSG levels For each cell line, a total of 4000 cells/well were seeded into 96-well plates

This specific criterion was applied to maintain a strict focus on synthesizing pro-tumorigenic mechanisms, rather than to negate the context-dependent, dual roles of ROS in cancer biology