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In analyses excluding individuals with no BMI information and using multiple imputation for BMI missing values, respective HRs were 0.89 (95% CI 0.26, 3.14) and 1.29 (95% CI 0.42, 3.92) (Table 2)
The addition of AMPLITUDE-O data refined evidence for cardiovascular benefits, in particular showing reduction in hospital admission for heart failure, and suggested exendin-4-based compounds lower risks as well as human-based GLP-1 receptor agonists, Naveed Sattar, MD, PhD, professor of metabolic medicine at the University of Glasgow in the U.K., and colleagues wrote
Wuttke, W., Jarry, H., Haunschild, J., Stecher, G., Schuh, M., & Seidlova-Wuttke, D
While some studies show that ALA supplements can help people who are overweight lose small amounts of weight, it doesn't appear to affect their waist size