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Diabetes Obes Metab (2021) 23:11624

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allow it to air dry

Mice fed a HFD gained significantly more mass than mice on the conventional diet and administration of JA1 significantly reduced animal mass in mice fed a HFD (Fig

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Notably, caloric restriction (CR) and moderate weight loss (approximately 510%) improve insulin sensitivity despite the accompanying loss of muscle mass, and the observed reduction appears to result primarily from increased proteolysis rather than reduced protein synthesis