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Retatrutide is an investigational triple-agonist that is not currently FDA-approved for clinical weight-loss use

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In addition to structural damage, sexual morbidity remains a major but often underappreciated consequence of brachytherapy [107, 113]

The characteristic changes of GLP-1 face include 4,5 : Facial volume loss, particularly in the midface Periocular hollowing and periorbital volume depletion Dermal thinning with loss of collagen and elastin fibers Decreased skin elasticity leading to redundant skin folds Accelerated appearance of aging As a result of these facial changes, GLP-1 agonist medications can result in an older, haggard and tired looking appearance