Among people without diabetes the shift was even more pronounced, with semaglutide rising from 8% to 65% of all GLP-1 use over the same period
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But because the landscape around compounded GLP-1 medications has shifted dramatically since the FDA resolved the semaglutide shortage in February 2025, and what was once a straightforward decision now involves regulatory gray areas, legal battles, and quality control questions that most people never expected to navigate
How to Cite Universa Medicina , 36 (3), 179-186
While individual cases of increased suicidality following GLP-1 receptor agonist use have been reported, our large cohort study found no such association and instead suggested a decreased risk of suicidal behavior in adolescents receiving this treatment, Kerem told Healio
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