Common side effects during the first month are: Gastrointestinal issues (most frequent) side effect: Nausea Vomiting Diarrhoea Constipation Bloating and Gas Decreased appetite while this is desired for weight loss, sometimes it can be extreme and lead to difficulty in eating even normal portions Fatigue Headache Dizziness Injection site reactions such as redness, swelling or irritation around the site These most common side effects of Wegovy are present in the first month as the body gets used to the medicine and also around dose changes, but they then gradually reduce with consistent Wegovy use
GLP-1 drugs such as Wegovy and Ozempic (semaglutide) and Zepbound (tirzepatide) may offer benefits that extend beyond aiding in weight loss in people who have type 2 diabetes or obesity
Whats Normal vs Whats Not Usually normal and temporary: Mild headaches Injection site irritation Short-term fatigue Minor water retention May require dose adjustment: Ongoing headaches Persistent swelling Repeated nausea Noticeable appetite changes Should be discussed promptly with a provider: Side effects lasting longer than two weeks Symptoms that worsen over time Anything that interferes with daily activities Who Is More Likely to Experience Side Effects
Semaglutide is a synthetic 31-amino-acid polypeptide analog of the endogenous glucagon-like peptide-1 (GLP-1), belonging to the class of drugs labeled glucagon-like peptide-1 receptor agonists (GLP-1 RAs)
Most patients experience changes in how their digestive system operates, though the severity varies widely
It takes a few months to reach the target dose, and you may experience side effects like nausea, vomiting, and diarrhea