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The second participant had a non-serious AE of increased creatine phosphokinase (CPK) after initiation of a vigorous strength training program and discontinued study drug due to protocol-specified criteria
J Soc Biol
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Improved Mobility : Weight loss enhances mobility and flexibility, making it easier for individuals to engage in physical activities
4 Accordingly, the manufacturer prescribing information for all currently available GLP-1 RAs includes a warning for increased risk of hypoglycemia when used in combination with an insulin secretagogue or insulin 5-11 and state that reducing the dose of the insulin secretagogue or insulin may be necessary to prevent hypoglycemia
Obesity trials use weight as the primary endpoint
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