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The most common side effects of tirzepatide are gastrointestinal, including nausea (12-30%), diarrhea (7-22%), vomiting (2-10%), constipation (5-17%), and abdominal pain (5-10%)

GLP-1 receptor agonists slow gastric emptying, which has been hypothesized to affect pancreatic function, though this connection remains speculative and lacks supporting clinical evidence

Table 1 of this article summarizes the results of industry-sponsored randomized controlled trials

Traditional braces use stock brackets, which require more mid-course corrections and more office visits

Doctors can recommend methods for losing weight that clinical trials have demonstrated to be effective and safe

2019 May 15;18(5):1171-1184