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Benefits of semaglutide Up to 15% body weight loss maintained over 2 years 2 Improved blood sugar control and lower A1C Reduced risk of cardiovascular events in high-risk individuals 8 May support metabolic conditions like high cholesterol or hypertension Compounded and brand-name semaglutide options PlushCare physicians may prescribe brand-name GLP-1 medications, as well as compounded semaglutide when listed as available by the FDA