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One of MOTS-C's downstream effects is increasing intracellular NAD+ utilization the mitochondria are running harder, so they're consuming more of the NAD+ pool
Konukoglu D, Turhan MS, Ercan M, Serin O
(2016) found that acute fluoxetine administration in prepubertal female rats resulted in increased estradiol concentrations, whereas subchronic administration led to increased serotonin concentrations in the ovaries, a decrease in the number of ovulations, a greater number of atretic follicles, and oocyte fragmentation
Worse yet, a 2024 study suggests that TB-500 itself may not even be the active compound, but that its healing activity might come from a smaller piece it breaks down into in the body
GLP-1 exhibits several pleiotropic effects beyond their primary role in glycemic control
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