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For example, prominin-2 (PROM2)-mediated exosomes can promote ferroptosis resistance by exporting ferritin-containing multivesicular bodies and facilitating iron efflux, thereby reducing the intracellular labile iron pool

178 Furthermore, cyst(e)inase, a glutathione inhibitor that degrades cysteine and cystine, reduces tumor progression by elevating ROS levels and inducing tumor cell-selective ferroptosis

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Enhanced intracellular reactive oxygen species by photodynamic therapy effectively promotes chemoresistant cell death

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