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If you feel tired or weak: this usually means you are under-eating overall or consistently missing protein

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The weight loss achieved with GLP-1 therapy also reduces risks for heart disease, stroke, and type 2 diabetes, offsetting minor temporary discomfort

In 2005 a synthetic version called exenatideinspired by a more stable compound found in Gila monster venombecame the first GLP-1 receptor agonist to be approved by the U.S