Animal studies show that GABA receptor agonists effectively reduce mortality in a mouse model of Covid.[ref] GABA and Autoimmune Diseases: With the inhibitory effect of GABA on immune response, researchers are now looking at the possibility of using GABA or a GABA-receptor drug to modulate the immune response in autoimmune diseases.[ref] Much of the research on GABA in the immune system and autoimmune diseases is very recent, with much of it only in animal models of diseases at this point
PloS Biol
Effects of intracerebroventricular injection of glucagon like peptide-1 and its related peptides on serotonin metabolism and on levels of amino acids in the rat hypothalamus
Hauge, C., Breitschaft, A., Hartoft-Nielsen, M
In another study involving Type 2 Diabetes patients, the consumption of milk kefir consisting of Lactobacillus acidophilus , Lactococcus casei , Streptococcus thermophilus , and Bifidobacterium lactis for two months showed a 2.12-fold decrease in Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), which is clinically relevant as it suggests an improvement in insulin sensitivity and potentially can prevent a sudden spike in blood sugar level (Alihosseini et al., 2017)
Available as Mounjaro and Zepbound