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evaluated the influence of GLP-1 in 5xFAD mice, where liraglutide restored astrocytic mitochondrial function and prevented neuronal loss
However, limitations included the restricted inclusion criteria (eGFR range of 2075 mL/min/1.73 m 2 and albuminuria requirements), which limit generalizability to patients with higher or lower eGFR or preserved eGFR without albuminuria
In hESCs, genome-wide analysis found that histone modifications regulate gene expression by altering chromatin structure to facilitate decidualization (54)
Efficacy of high-dose liraglutide as an adjunct for weight loss in patients with prior bariatric surgery
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