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The Phase 2/3 WONDERS trials were placed on clinical hold in June 2025 after some participants developed low CD4+ T-cell counts and reduced total white blood cell counts

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A third factor rarely gets discussed

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Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis

Subcutaneous injections are given just below the skin surface, usually in the abdomen, thigh, or upper arm