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It binds to three different types of receptors: GLP-1, GIP, and glucagon receptors
47 Another analysis reported that semaglutide use in individuals with T2DM increased the risk of developing GI adverse events by 2.14 times compared with control groups, although it was emphasized that the vast majority of these side effects were mild
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GLP-1 receptor activation slows gastric emptying, reduces appetite through hypothalamic signaling, and enhances insulin secretion in response to food
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