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The docking analyses revealed that the positioning of the GSH-thiolate in relation to C-2 and O-3 of the docked substrates could enable an acidbase mechanism of dehydration or tautomerization, in which the GSH cofactor acts as a proton-relay system (Fig

Endothelial dysfunction during acute methionine load in hyperhomocysteinaemic patients

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Of the 119/48 total intermolecular NOEs for p53 TAD2 -FOXO4-DRI/p53 TAD2 -FOXO4 FH complexes only 19/2 NOEs could be assigned unambiguously

156 Importantly, pregabalin can damage the retinal nerve and is therefore contraindicated for those with diabetic retinopathy or glaucoma