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Effect of chronic apocynin treatment on nitric oxide and reactive oxygen species production in borderline and spontaneous hypertension

22,56,57 Cardiovascular diseases and related risk factors (e.g., hypertension, atherosclerosis) impair blood flow to peripheral nerves, worsening neuropathic symptoms

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In wound healing, fibroblasts play a significant role because they produce extracellular matrix proteins such as collagen and fibrin (1)

however, symptoms such as nausea, vomiting, dyspnea, and abdominal pain were not observed