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Therefore, assay for reduced activity of this enzyme, in red blood cell lysates, is highly diagnostic in cases of suspected thiamine deficiency

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We know that caloric restriction and other forms of fasting induce changes in the metabolism of these cells, forcing them to reduce their reliance on glucose and increase the use of mitochondrial oxidative pathways

10.1016/j.bbagen.2014.12.001 Biochim Biophys Acta