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This viewpoint promotes a transition from viewing GLP-1 RAs in a disease-specific manner to a more comprehensive understanding of whether these drugs impact various aging hallmark processes, including mitochondrial dysfunction, impaired proteostasis, and the decline in stem and progenitor cell functionelements that contribute to the diminished functional reserve seen with aging
Tirzepatide is a medication initially developed for the treatment of type 2 diabetes
Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
It plays several important roles in metabolic health, including signalling to your brain that you're full, slowing down how quickly food leaves your stomach, and helping your pancreas release the right amount of insulin to manage blood sugar levels
However, tolerability, discontinuation rates, and comparative efficacy will be key watchpoints