Synthetic BPC-157 is chemically defined to a single sequence (GEPPPGKPADDAGLV, 1419.5 Da), whereas the native protein is studied as part of a heterogeneous gastric proteome (Sikiric et al., 2018
Accessed November 4, 2024
Therefore, it seems interesting and worthy to review this topic, which has captured the interest of many basic and clinical investigators for many years, and gives the opportunity to present their most recent findings, including development of new medicines, pharmacological tools and new approaches to protect or/and heal GI-tract acute injuries and chronic ulcers
doi: 10.1016/j.bbih.2020.100047 514 MaesMMihaylovaIKuberaMLeunisJ-CTwiskFNMGeffardM
3, 61-90 degrees
Published literature includes over 100 studies examining its effects in various in-vitro and animal model systems, with research groups investigating gastrointestinal cytoprotection, tendon and ligament tissue models, and neurological signaling pathways