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In type 2 diabetes this signaling degrades, and incretin-based agents are designed to restore it pharmacologically

Glutathione peroxidase 1 Glutathione peroxidase 1 , also known as GPx1 , is an enzyme that in humans is encoded by the GPX1 gene on chromosome 3

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258 Thus, HDAC9 controls autophagy at multiple levels through histone deacetylation and TFEB modulation, thereby linking chromatin dynamics to disease and development