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Patients with diabetic retinopathy, diabetic neuropathy, and both diabetes and hyperlipidemia had a significantly lower total and free carnitine level compared with the diabetic patients without complications or co-morbidities

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Even if the compound enters the target tissue/organ, it may not reach the active sites of oxidative damage (e.g., mitochondria)

Gujrati H, Ha S, Wang BD Deregulated microRNAs involved in prostate cancer aggressiveness and treatment resistance mechanisms