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They approximated randomization by balancing more than 80 characteristics across groups
However, immediately is context-dependent
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This approach makes sense because depression involves multiple brain chemical systems
We now have a breakthrough class of drugs that can achieve profound weight loss equivalent to bariatric surgery, along with the side benefits of reducing cardiovascular risk factors (hypertension and hyperlipidemia), improving glucose regulation, reversing fatty liver, and the many detrimental long-term effects of obesity such as osteoarthritis and various cancers
This can be beneficial for individuals with malabsorption issues or those who have difficulty absorbing essential nutrients from their diet
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