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Moreover, individualized dosing strategies can help mitigate the risk of common side effects, such as nausea and gastrointestinal discomfort, which are often associated with higher doses in standard treatment protocols
GLP-1RAs are essential for preventing fractures in people with T2DM because they greatly increase bone mass, trabecular and cortical architecture, and total bone strength
These results may not translate to human outcomes
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doi: 10.1002/ejp.621 7 BurgunderJ
Of 264,708 individuals in the Danish database, the researchers identified 1,737 incident glaucoma cases that were matched to 8,685 controls without glaucoma, all of whom were above 21 years old, had no history of glaucoma and were treated with metformin and a second-line antihyperglycemic drug formulation (a GLP-1RA)
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