TB-500 is a synthetic fragment of Thymosin Beta-4, more often studied in cell-migration and soft-tissue models
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So far the medication is great
Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs
Similarly, effects on children and adolescents are unknown, and use in these populations cannot be recommended
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