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17 August 2018
Engineered with a 13-amino acid extension, it delivers sustained anabolic signaling for muscle growth, recovery, and metabolic optimization beyond what natural IGF-1 can achieve
Weight loss of 5-10% can make a profound difference [25-28]
Also, retatrutide isn't FDA-approved, while Ozempic and Mounjaro are, so "better" depends on whether you prioritize efficacy or regulatory approval and availability
This protocol works because it attacks GLP-1 constipation from every angle simultaneously
SURMOUNT-5 Head-to-Head In 2025, Eli Lilly published the SURMOUNT-5 trial directly comparing tirzepatide (15 mg) and semaglutide (2.4 mg) in adults with obesity over 72 weeks
